Tranexamic Acid & Etamsylate Tablets – An accurate combination of two medicines, Tranexamic and Etamsylate, these tablets are used in the treatment of Menorrhagia; heavy or excessive menstrual bleeding. It is also used to stop Local Fibrinolysis, i.e., abnormal breakdown of blood clots, and Postoperative Hemorrhage, i.e., excessive bleeding after surgery. Available with the brand name Nexic-E, these tablets are manufactured by the Best Tranexamic Acid & Etamsylate Tablet Manufacturer, Moruf Life Sciences.
Mechanism of Action
Tranexamic Acid
Tranexamic Acid is an anti-fibrinolytic agent.
It inhibits the activation of plasminogen to plasmin – an enzyme responsible for breaking down blood clots.
By blocking this activity, it stabilizes clots and prevents excessive bleeding.
It slows down clot breakdown during menstruation, thereby reducing blood loss significantly.
Etamsylate
Etamsylate is a hemostatic (bleeding control) agent.
It improves platelet adhesion, helping platelets stick together more effectively.
Strengthens blood vessels and enhances the formation of stable blood clots.
Reduces capillary bleeding and prevents clot-dissolving chemicals from disrupting clot formation.
Dosage & Administration
Dosage must always be directed by the doctor. General recommended dosage for adults are
1 tablet two to three times a day, depending on the severity of bleeding
Should be taken with water, after meals to avoid stomach discomfort
Duration of therapy is usually 3–5 days during heavy bleeding episodes
Do NOT exceed the prescribed dosage. The dosage may vary based on:
Patient’s bleeding condition
Medical history
Kidney function
Concomitant medication
Side Effects
Most side effects are mild and temporary. Common side effects include:
Nausea or vomiting
Headache
Stomach discomfort
Diarrhea
Dizziness
Fatigue
Skin rash (rare)
Leg cramps
Essential Instructions
Taking Tranexamic Acid & Etamsylate Tablets exactly as prescribed by the doctor or gynecologist will help the woman in getting rapid relief from heavy menstrual bleeding. Thus, take this medicine correctly in accordance with the directions of the doctor. Moreover, follow the tips and instructions mentioned below to remain safe from the unwanted or troublesome negative effects:
Take Tranexamic Acid & Etamsylate Tablets only if you experience heavy or unusual menstrual bleeding, only if the cause is determined by the doctor.
Do not take these tablets if you are allergic to Tranexamic, Etamysylate, or any other present ingredients of the medicine.
If you are using birth control pills including the vaginal ring, patch, or IUD (intrauterine device), make sure to inform your doctor about the risk of Deep Vein Thrombosis (a condition in which blood clot develops in deep veins, especially in the legs) may develop.
Consuming alcohol while on the treatment with Tranexamic Acid & Etamsylate Tablets may increase the risk of unusual side effects. It is advised for women to avoid alcoholic beverages to remain safe from such side effects.
It is better to not take these tablets if you have a history of kidney failure, seizures, porphyria, thrombosis, and disseminated intravascular coagulation (a disease where blood clots form throughout the body).
Frequently Asked Questions (FAQs)
A: These tablets are used to treat heavy menstrual bleeding (menorrhagia), postoperative bleeding, and bleeding caused by local fibrinolysis. They help stabilize blood clots and reduce excessive blood loss.
A: Tranexamic Acid prevents clot breakdown, while Etamsylate enhances platelet adhesion and strengthens blood vessels. Together, they provide faster and more effective bleeding control.
A: No, they should be taken only during heavy bleeding episodes and strictly under medical supervision. They are not recommended for routine monthly use.
A: Many patients notice improvement within a few hours. Full effectiveness is usually seen within 24–48 hours.
A: They are classified as Category B, meaning no proven harm in animal studies. However, pregnant women should use them only if prescribed by a doctor.
A: Small amounts may pass into breast milk. Breastfeeding women should take it only after consulting their gynecologist.
A: Common side effects include nausea, headache, dizziness, stomach discomfort, and diarrhea. Rare serious effects, such as vision changes or blood clots, require immediate medical attention.
A: Women with a history of thrombosis, stroke, severe kidney disease, porphyria, seizures, or clotting disorders should avoid using this medication unless advised by a doctor.
A: Combining them with hormonal contraceptives may increase the risk of blood clots. Inform your doctor if you use pills, patches, or IUDs before starting this medicine.
A: Alcohol may increase dizziness and stomach irritation. It is best to avoid alcohol during treatment.
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